GLP-1
GLP-1 – definition and facts in our glossary. Basis for Ozempic/Wegovy.
What is GLP-1?
GLP-1 also acts by inhibiting glucagon secretion, a hormone that raises blood sugar.
How does it work in the body?
GLP-1 works by binding to specific receptors in the body, resulting in several important effects:
Scientific benefits
Research has shown that GLP-1 and its analogues offer several health benefits:
- A meta-analysis published in The Lancet demonstrated that these agents significantly improved glycaemic control.
- A study in the New England Journal of Medicine showed that participants using Wegovy lost on average 15% of their body weight.
Dosage and recommendations
The dose of GLP-1 analogues, such as Ozempic and Wegovy, can vary depending on the individual’s needs and the medication’s specifications. Treatment usually starts with a low dose that is gradually increased to minimise side effects. It is important to follow the doctor’s recommendations carefully to achieve the best results.
Best sources and forms
It is important to discuss with a doctor whether these treatments are suitable for you.
Side effects and warnings
As with all medications, GLP-1 analogues can cause side effects. Common side effects include:
- Nausea
- Stomach cramps
- Diarrhoea
- Constipation
Serious side effects are rare but may include pancreatitis and kidney problems. It is important to inform your doctor of any side effects and discuss risks before starting treatment with GLP-1 analogues.
Frequently asked questions
What is the difference between GLP-1 and GLP-1 analogues?
GLP-1 is a natural hormone produced in the body, whereas GLP-1 analogues are synthetically produced medications that mimic the hormone’s action and are used to treat type 2 diabetes and obesity.
Are GLP-1 injections safe to use?
GLP-1 injections are generally safe for most people, but like all medications, they can have side effects. It is important to discuss with a doctor before starting treatment.
How long does it take to see results from GLP-1 analogues?
Are GLP-1 analogues expensive?
The cost of GLP-1 analogues can vary depending on insurance coverage and where you live. It is advisable to check with your insurer to see what is covered.